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位置: 首页> 品牌> Sigma-Aldrich> Anti-SLIT2 antibody produced in rabbit

Anti-SLIT2 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
HPA023088
规格纯度
Prestige Antibodies?Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2
价格
6389.73 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
Anti-SLIT2 antibody produced in rabbit
Anti-Slit-2
Anti-Slit homolog 2 protein
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

SLIT2 (slit guidance ligand 2) is a secreted glycoprotein and associates with ROBO (roundabout) receptor. SLIT2 mRNA is present in the brain, spinal cord, and thyroid. The gene is mapped to human chromosome 4p15. It is also referred to as SLIL3.

免疫原

Slit homolog 2 protein Precursor recombinant protein epitope signature tag (PrEST)

应用

Anti-SLIT2 antibody produced in rabbit, a Prestige Antibody, is developed and validated by the Human Protein Atlas (HPA) project (www.proteinatlas.org). Each antibody is tested by immunohistochemistry against hundreds of normal and disease tissues. These images can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. The antibodies are also tested using immunofluorescence and western blotting. To view these protocols and other useful information about Prestige Antibodies and the HPA, visit sigma.com/prestige.

生化/生理作用

The SLIT2 (slit guidance ligand 2)/ROBO (roundabout) complex is crucial for the axon guidance and neural crest cell migration. The complex also enhances intestinal tumorigenesis. On the other hand, inactivation of SLIT2 is associated with the presence of dysplastic lesions of head and neck. Mutations in SLIT2 are linked with high risk of congenital anomalies of the kidney and urinary tract (CAKUT).

特点和优势

Prestige Antibodies?are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies?to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:

  • IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
  • Protein array of 364 human recombinant protein fragments.

联系

Corresponding Antigen APREST74497.

外形

Solution in phosphate-buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide

法律信息

Prestige Antibodies is a registered trademark of sigma-aldrich Co. LLC

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

人类蛋白质图谱编号 HPA023088 Human Protein Atlas characterization data

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
半岛bd体育手机客户端 线 Prestige Antibodies?Powered by Atlas Antibodies
形式 buffered aqueous glycerol solution
species reactivity human
包装 antibody small pack of 25 μL
technique(s) immunohistochemistry: 1:50- 1:200
免疫原序列 LYINSELQDFQKVPMQTGILPGCEPCHKKVCAHGTCQPSSQAGFTCECQEGWMGPLCDQRTNDPCLGNKCVHGTCLPINAFSYSCKCLE
UniProt登记号 O94813
运输 wet ice
储存温度 ?20℃
Gene Information human ... SLIT2(9353)

安全信息

储存分类代码 10 - Combustible liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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