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位置: 首页> 品牌> Sigma-Aldrich> Anti-Slc22A17 Antibody

Anti-Slc22A17 Antibody

品牌
Sigma-Aldrich
货号
ABC846
规格纯度
from rabbit, purified by affinity chromatography
价格
5854.74 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-Slc22A17 Antibody
Solute carrier family 22 member 17, 24p3 receptor, 24p3R, Brain-type organic cation transporter, Lipocalin-2 receptor, Neutrophil gelatinase-associated lipocalin receptor, NgalR, Slc22A17
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Solute carrier family 22 member 17, also known as 24p3 receptor (24p3R) or Brain-type organic cation transporter or Lipocalin-2 receptor or Neutrophil gelatinase-associated lipocalin receptor (NgalR), and encoded by the gene name SLC22A17 or BOCT or BOIT, is a family of organic anion and cation transporters (OATs, OCTs, OCTNs) that are expressed in brain. Each contain 12 predicted alpha-helical transmembrane domains (TMDs) and one large extracellular loop between TMDs 1 and 2. Transporters of the SLC22 family function in different ways such as uniporters that mediate facilitated diffusion in either direction (OCTs), as anion exchangers (OAT1, OAT3 and URAT1), and as Na(+)/l-carnitine cotransporter (OCTN2). Slc22 family members participate in the absorption and/or excretion of drugs, xenobiotics, and endogenous compounds in intestine, liver, and kidney, and perform homeostatic functions in brain and heart. Mutations in the Slc22 family may cause specific diseases such as primary systemic carnitine deficiency or idiopathic renal hypouricemia and may change drug absorption or excretion. Recent studies show the expression of Slc22A17 as receptor for Lipocalin 2 is relatively high in hematopoietic stem cells.

免疫原

KLH-conjugated synthetic peptide corresponding to the C-terminus of human Slc22A17.

应用

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected Slc22A17 in rat kidney tissue.
Anti-Slc22A17 Antibody is an antibody against Slc22A17 for use in western blotting & immunofluorescence.

质量

Evaluated by Western Blotting in SK-N-SH cell lysate with and without blocking peptide.

Western Blotting Analysis: 1 μg/mL of this antibody detected Slc22A17 in SK-N-SH cell lysate with and without blocking peptide.

目标描述

~60 kDa observed. Uncharacterized bands may be observed in some lysate(s).

外形

Antigen Affinity Purified

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity human
technique(s) immunofluorescence: suitable
western blot: suitable
UniProt登记号 Q8WUG5
运输 wet ice
Gene Information human ... SLC22A17(51310)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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