半岛bd体育手机客户端 说明
一般描述
Special AT-rich sequence-binding protein 2 (SATB2) contains 2 CUT DNA-binding domains and one homeobox DNA binding domain belonging to the CUT homeobox family. SATB2 binds to DNA at the nuclear matri or scaffold-associated regions. SATB2 is highly expressed in adult brain, moderately expressed in fetal brain, and weakly expressed in adult liver, kidney, and spinal cord. Mutations in SATB2 have been associated with cleft palate.
特异性
This antibody recognizes the N-terminus of SATB2.
免疫原
KLH-conjugated linear peptide corresponding to the N-terminus of human SATB2.
Epitope: N-terminus
应用
Research Sub Category
Transcription Factors
Detect Special AT-rich sequence-binding protein 2 using this rabbit polyclonal antibody, Anti-SATB2 Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.
Research Category
Epigenetics & Nuclear Function
Immunohistochemistry Analysis: 5 ?g/mL from a representative lot detected SATB2 in human brain tissue.
Immunofluorescence Analysis: 20 μg/mL from a representative lot detected SATB2 in human brain cells.
质量
Evaluated by Western Blotting in mouse brain tissue lysate.
Western Blotting Analysis: 4 ?g/mL of this antibody detected SATB2 in 15 ?g of mouse brain tissue lysate.
目标描述
~90 kDa observed
外形
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Mouse brain tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | human, mouse |
technique(s) | immunofluorescence: suitable immunohistochemistry: suitable (paraffin) western blot: suitable |
UniProt登记号 | Q9UPW6 |
运输 | wet ice |
Gene Information | human ... SATB2(23314) |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich