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Anti-Rab9 from rabbit

品牌
Sigma-Aldrich
货号
R5279
规格纯度
~1 mg/mL, affinity isolated antibody, buffered aqueous solution
价格
4731.57 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-Rab9 from rabbit
Anti-Ras-Related Protein Rab9
Anti-Ras-Associated Protein Rab9
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Rab9 is a member of the Rab family of guanosine triphosphatases (GTPases). Rab9 GTPase is localized predominantly to late endosomes. Rab proteins contain conserved regions involved in guanine nucleotide binding, and hypervariable COOH-terminal domains with a cysteine motif implicated in subcellular targeting.

免疫原

synthetic peptide corresponding to amino acid residues 188-200 of human Rab9, conjugated to KLH.

应用

Anti-Rab9 from rabbit has been used in immunoblotting and immunofluorescence.

生化/生理作用

Rab9 GTPase is required for the transport of mannose 6-phosphate receptors (MPRs) from endosomes to the trans-Golgi network (TGN). Rab9 GTPase in its GTP bound conformation binds specifically to an effector protein named p40 that stimulates the transport of mannose 6-phosphate receptors (MPRs) from endosomes to the TGN. Rab9 also interacts with the vesicle cargo selection protein TIP47 (tail-interacting protein of 47 kDa). This interaction is required for Rab9 stability on late endosomes. Anti-Rab9 antibodies may be used as a marker for late endosomes.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD03097193

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 200
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen ~23 kDa
species reactivity rat, human, mouse
浓度 ~1 mg/mL
technique(s) indirect immunofluorescence: 5-10 μg/mL using rat NRK and mouse NIH3T3 cells fixed and permeabilized with 3% paraformaldehyde followed by 0.4% saponin
western blot: 5-10 μg/mL using whole extract of human A431 cells
UniProt登记号 P51151
运输 dry ice
储存温度 ?20℃
Gene Information human ... RAB9A(9367)
mouse ... Rab9(56382)
rat ... Rab9a(84589)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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