Anti-PTBP2 Antibody

半岛bd体育手机客户端 说明

一般描述

Polypyrimidine tract-binding protein 2 (PTBP2) is also known as Neural polypyrimidine tract-binding protein, Neurally-enriched homolog of PTB and PTB-like protein. PTBP2 is a RNA-binding protein which targets intronic polypyrimidines and negatively regulates pre-mRNA, exonic splicing. PTBP2 also has a role in translational regulation. PTBP2 is mainly expressed in brain, but is also found in heart and skeletal muscle. Isoforms 1 and 2 are specifically expressed in neuronal tissues.

特异性

This antibody recognizes the N-terminus of PTBP2.

免疫原

KLH-conjugated linear peptide corresponding to the N-terminus of human PTBP2.
Epitope: N-terminus

应用

Research Sub Category
Transcription Factors
Anti-PTBP2 Antibody is a highly specific rabbit polyclonal antibody, that targets Polypyrimidine tract-binding protein 2 & has been tested in western blotting & IP.
Western Blotting Analysis: 0.5 ?g/mL from a representative lot detected PTBP2 in 10 ?g of rat brain cortex tissue lysate.
Immunoprecipitation Analysis: 10ug from a representative lot immunoprecipitated PTBP2 in 500 ?g of P19 cell lysate.
Research Category
Epigenetics & Nuclear Function

质量

Evaluated by Western Blotting in human cortex tissue lysate.

Western Blotting Analysis: 0.5 ?g/mL of this antibody detected PTBP2 in 10 ?g of human cortex tissue lysate.

目标描述

~57 kDa observed. Uncharacterized band(s) may appear in some lysates.

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Human cortex tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
纯化方式	affinity chromatography
species reactivity	human, rat, mouse
species reactivity (predicted by homology)	gorilla (based on 100% sequence homology), bovine (based on 100% sequence homology), rhesus macaque (based on 100% sequence homology), canine (based on 100% sequence homology)
technique(s)	immunoprecipitation (IP): suitable western blot: suitable
NCBI登记号	NP_067013
UniProt登记号	Q9UKA9
运输	wet ice
Gene Information	human ... PTBP2(58155)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable