Anti-Neuropilin-1 Antibody

半岛bd体育手机客户端 说明

一般描述

Neuropilin-1 is a type 1 membrane protein with three distinct functions. First, it can mediate cell adhesion via a heterophilic molecular interaction. Second, in neuronal cells, neuropilin-1 binds the class 3 semaphorins, which are neuronal chemorepellents, and plays a role in the directional guidance of axons. It is expected to form complexes with the plexinA subfamily members and mediate the semaphorin-elicited inhibitory signals into neurons. Third, in endothelial cells, neuropilin-1 binds a potent endothelial cell mitogen, vascular endothelial growth factor (VEGF)165, and regulates vessel formation.

特异性

This antibody recognizes Neuropilin-1.

免疫原

This antibody is generated from rabbits immunized with a His-tagged partial recombinant rat Neuropilin-1.
Epitope: Unknown

应用

Research Category
Neuroscience
Research Sub Category
Growth Cones & Axon Guidance
This Anti-Neuropilin-1 Antibody is validated for use in WB, IH, IP, IF for the detection of Neuropilin-1.

质量

Evaluated by Western Blot in PC12 cell lysate.
Western Blot Analysis: : 1:1,000 dilution of this antibody detected Neuropilin 1 on 10 ?g of PC12 cell lysate.

目标描述

130 kDa

外形

Unpurified
Rabbit serum in buffer containing 0.05% sodium azide.

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
PC12 cell lysate

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	serum
antibody product type	primary antibodies
克隆	polyclonal
species reactivity	rat, mouse
species reactivity (predicted by homology)	human (94%)
technique(s)	immunofluorescence: suitable immunohistochemistry: suitable immunoprecipitation (IP): suitable western blot: suitable
同位素/亚型	IgG
NCBI登记号	NP_659566.1
UniProt登记号	Q9QWJ9
运输	wet ice
Gene Information	human ... NRP1(8829)

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 1