Anti-HMGA2 antibody produced in rabbit

半岛bd体育手机客户端 说明

一般描述

High mobility group A2 (HMGA2) protein is a non-histone architectural transcription factor. This protein belongs to the high-mobility group adenine/thymine (AT)-hook (HMGA) family. HMGA2 is expressed in the mesenchyme prior differentiation and tumors of epithelial origin. The HMGA2 gene is located on the human chromosome at 12q14.3.

免疫原

Recombinant fragment corresponding to a region within amino acids 1 and 109 of HMGA2 (Uniprot ID#P52926)

应用

Anti-HMGA2 antibody produced in rabbit has been used in immunohistochemistry (1:250), (1:100), (1:4000).

生化/生理作用

High mobility group A2 (HMGA2) protein is involved in regulating the activity of various genes by binding to the adenine/thymine (AT)-rich sequences present in the minor groove of B?form DNA. This protein plays a role in many biological processes such as the DNA damage repair process, senescence, apoptosis, and cell cycle process. HMGA2 protein also plays a role in epithelial-mesenchymal transition and telomere restoration. Overexpression of HMG2A gene is observed in metastatic lung adenocarcinoma.

特点和优势

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外形

1XPBS, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES

NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
偶联物	unconjugated
抗体形式	purified immunoglobulin
antibody product type	primary antibodies
克隆	polyclonal
形式	liquid
分子量	12 kDa
species reactivity	rat, human, mouse
浓度	0.7 mg/mL
technique(s)	ChIP: suitable immunofluorescence: suitable immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable immunoprecipitation (IP): suitable western blot: 5000-50000
UniProt登记号	P52926
运输	wet ice
储存温度	?20℃
Gene Information	human ... HMGA2(8091)

安全信息

象形图
警示用语：	Warning
危险声明	H317 - H412
预防措施声明	P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
危险分类	Aquatic Chronic 3 - Skin Sens. 1
储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable