半岛bd体育手机客户端 说明
一般描述
Glutamate receptor interacting protein-1 (GRIP-1) is a multi-PDZ domain scaffold protein and a member of the steroid receptor coactivator (SRC) family of proteins. GRIP-1 interacts and maneuvers kinesin heavy chains to dendrites by acting as the power source for AMPA receptors. During initial stages of embryonic development, GRIP-1 is essential for typical cell-matrix interactions.
特异性
This antibody recognizes GRIP-1 at the C-terminus.
免疫原
KLH-conjugated linear peptide corresponding to the C-terminus of rat GRIP-1.
Epitope: C-terminus
应用
Research Sub Category
Signaling Neuroscience
Research Category
Neuroscience
Detect GRIP-1 using this Anti-GRIP-1 Antibody, C-terminus validated for use in WB, IP, IH(P).
Immunoprecipitation Analysis: 10 ?g from a previous lot immunoprecipitated GRIP-1 from rat brain cytosol tissue lysate.
Immunohistochemistry Analysis: 1:300 dilution from a previous lot detected GRIP-1 in rat brain cells.
质量
Evaluated by Western Blot in rat brain cytosol tissue lysate.
Western Blot Analysis: 0.05 ?g/mL of this antibody detected GRIP-1 on 10 ?g of rat brain cytosol tissue lysate.
目标描述
~121 kDa observed
联系
Replaces: 06-986
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Rat brain cytosol tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | rat |
species reactivity (predicted by homology) | chimpanzee (based on 100% sequence homology), human (based on 100% sequence homology), mouse (based on 100% sequence homology) |
technique(s) | immunohistochemistry: suitable (paraffin) immunoprecipitation (IP): suitable western blot: suitable |
NCBI登记号 | NP_114458 |
UniProt登记号 | P97879 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich