Anti-Endothelin B Receptor antibody produced in rabbit

半岛bd体育手机客户端 说明

免疫原

synthetic peptide corresponding to the N-terminal extracellular domain of human endothelin B receptor, conjugated to KLH. The immunizing peptide has 79% homology with the mouse gene and 84% homology with the rat gene.

应用

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Anti-Endothelin B Receptor antibody produced in rabbit is suitable for the following applications:

• Immunocytochemistry at a concentration of 4-11μg/mL using human adrenal tissue
• Immunohistochemistry (formalin-fixed, paraffin-embedded sections) at a concentration of 4-11μg/mL using human adrenal tissue
• Western blotting
• Immunofluorescence

生化/生理作用

EDNRB Endothelin receptor type B (ETB) is a protein encoded by the EDNRB gene in humans. It plays a pivotal role in oesophageal cancer and may act as a therapeutic target for this intractable malignancy. It has a novel role in oligodendroglioma proliferation and acts as a potential therapeutic alternative for oligodendrogliomas. Lower expression of ETB receptor responsiveness is associated with polycystic ovary syndrome (PCOS) and may reflect lower endothelial-mediated vasodilatation independent of generally lower vascular reactivity.

外形

Solution in phosphate buffered saline, pH 7.7, containing 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD00675241
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	200
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	human
technique(s)	immunocytochemistry: 4-11 μg/mL using human adrenal tissue immunohistochemistry (formalin-fixed, paraffin-embedded sections): 4-11 μg/mL using human adrenal tissue
UniProt登记号	P24530
运输	dry ice
储存温度	?20℃
Gene Information	human ... EDNRB(1910) mouse ... Ednrb(13618) rat ... Ednrb(50672)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable