Anti-α-Tubulin from chicken

半岛bd体育手机客户端 说明

一般描述

Tubulin α 1A (TUBA1A) is a member of α-tubulin gene family. It is encoded by the gene mapped to human chromosome 12q13.12. Tubulin α 1A is a vital structural subunit of microtubules that are temporarily expressed in almost all post-mitotic neurons during neuronal development. The encoded protein structure contains a core of two β-sheets enclosed by α-helices. TUBA1A is characterized with an amino-terminal domain having guanine nucleotide-binding region, an intermediate domain and a carboxy-terminal domain.

免疫原

Tubulin antibody was raised against a 16 amino acid peptide near the amino terminus of human Tubulin.

应用

Anti-α-tubulin from chicken has been used for Western blotting and immunohistochemistry.

生化/生理作用

Gene mutation of tubulin α-1A (TUBA1A) is observed in perisylvian asymmetrical polymicrogyria, polymicrogyria-like cortical dysplasia, and microlissencephaly in fetal cases. Alteration in the expression of the gene impairs neural migration and causes lissencephaly (LIS).

特点和优势

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联系

The action of this antibody can be blocked using blocking peptide SBP3500023.

外形

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD00145891
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	chicken
质量水平	100
偶联物	unconjugated
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	rat, human, mouse
technique(s)	indirect ELISA: suitable western blot: suitable
NCBI登记号	CAA25855
UniProt登记号	Q13748
运输	dry ice
储存温度	?20℃
Gene Information	human ... TUBA1A(7846)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	nwg
闪点(F)	Not applicable
闪点(C)	Not applicable