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位置: 首页> 品牌> Sigma-Aldrich> Anti-TCF12 antibody produced in rabbit

Anti-TCF12 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB3500566
规格纯度
affinity isolated antibody, buffered aqueous solution
价格
5045.46 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-TCF12 antibody produced in rabbit
Anti-HTF4
Anti-bHLHb20
Anti-HEB
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Transcription factor 12 (TCF12) is a class I member of helix-loop-helix (HLH) protein family, encodes for class II basic helix-loop-helix protein (bHLHb) transcription factor. In human chromosome, the gene TCF12 is localized on 15q21.3.

免疫原

TCF12 antibody was raised against a 19 amino acid peptide near the amino terminus of human TCF12.

应用

Anti-TCF12 antibody produced in rabbit has been used in immunoblotting.

生化/生理作用

Transcription factor 12 (TCF12) represses E-cadherin expression and thereby controls metastasis of colorectal cancer cells. TCF12 might play a role in controlling the proliferation of neural stem cells and progenitor cells. TCF12-TWIST1 (twist family bHLH transcription factor 1) heterodimers is required for the development of normal coronal suture. Mutations in the TCF12 heterodimer causes coronal craniosynostosis. TCF12 is critically required for regulating human mesodermal and hematopoietic specification in the early development. Mutations in TCF12 affects the transcriptional activity and leads to anaplastic oligodendroglioma, a rare brain tumor.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

联系

The action of this antibody can be blocked using blocking peptide SBP3500566.

外形

Supplied in PBS with 0.02% sodium azide.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity mouse, rat, human
technique(s) immunocytochemistry: suitable
indirect ELISA: suitable
western blot: suitable
NCBI登记号 AAH50556
UniProt登记号 Q99081
运输 dry ice
储存温度 ?20℃
Gene Information human ... TCF12(6938)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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