半岛bd体育手机客户端 说明
一般描述
LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues. LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins. Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while LRFN2 and LRFN5 expression was primarily restricted to more mature cells. LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery. It has been suggested that the LRFN proteins play a role in the developing and/or mature vertebrate nervous system.
特异性
This antibody is predicted to not cross-react with other members of the LRFN family.
免疫原
KLH-conjugated linear peptide corresponding to human LRFN4.
应用
Detect the LRFN4 protein using this Anti-LRFN4 validated for use in WB & IHC.
Immunohistochemistry Analysis: 2.5 ?g/mL from a representative lot detected LRFN4 in mouse brain tissue.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience
质量
Evaluated by Western Blot in mouse brain tissue lysate.
Western Blot Analysis: 1 ?g/mL of this antibody detected LRFN4 in 10 ?g/mL of mouse brain tissue lysate.
目标描述
~80 kDa observed. Uncharacterized bands may appear between ~40 and ~160 kDa in some lysates. The calculated molecular weight of this protein is 66 kDa, but can be observed at ~80 kDa due to high glycosylation.
外形
Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
Antigen Affinity Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Mouse brain tissue lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
半岛bd体育手机客户端 性质
| 质量水平 | 300 |
| 生物来源 | rabbit |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 纯化方式 | affinity chromatography |
| species reactivity | mouse |
| species reactivity (predicted by homology) | human (immunogen homology) |
| technique(s) | immunohistochemistry: suitable western blot: suitable |
| UniProt登记号 | Q6PJG9 |
| 运输 | wet ice |
| Gene Information | human ... LRFN4(78999) |
安全信息
| 储存分类代码 | 10 - Combustible liquids |
Sigma-Aldrich
m.cnreagent.com
