Anti-Bmf Antibody

半岛bd体育手机客户端 说明

一般描述

Bcl-2-modifying factor (Bmf) is a member of the Bcl-2 family containing one BCL2 homology domain 3. Members of this family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bmf associates with the dynein light chain 2 (DLC2) component of the myosin V motors and is sequestered by the cell′s actin cytoskeleton. Bmf is constitutively expressed in many tissues. There are 3 isoforms of Bmf. Isoform 1 is mainly expressed in B-lymphoid cells while isoform 2 and 3 are mainly expressed in B-CLL and normal B-cells.

特异性

This antibody recognizes the N-terminus of Bmf.

免疫原

KLH-conjugated linear peptide corresponding to the N-terminus of human Bmf.

应用

Immunocytochemistry Analysis: 10 ?g/mL from a representative lot detected Bmf in HeLa cells.
Detect Bcl-2-modifying factor using this rabbit polyclonal antibody, Anti-Bmf Antibody validated for use in western blotting & IHC.

质量

Evaluated by Western Blotting in HepG2 and HEK293 cell lysates.

Western Blotting Analysis: 1 ?g/mL of this antibody detected Bmf in 15 ?g of HepG2 and HEK293 cell lysates.

目标描述

~25 kDa observed

外形

Antigen Affinity Purified

分析说明

Control
HepG2 and HEK293 cell lysates

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
纯化方式	affinity chromatography
species reactivity	human
technique(s)	immunohistochemistry: suitable western blot: suitable
UniProt登记号	Q96LC9
运输	wet ice
Gene Information	human ... BMF(90427)

安全信息

储存分类代码	10 - Combustible liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable