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位置: 首页> 品牌> Sigma-Aldrich> ANTI-ACTIVIN RECEPTOR TYPE IA (ACVR1) (CENTER R147) antibody produced in rabbit

ANTI-ACTIVIN RECEPTOR TYPE IA (ACVR1) (CENTER R147) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1306388
规格纯度
IgG fraction of antiserum, buffered aqueous solution
价格
6662.67 *本价格含增值税费
促销
服务
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数量
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半岛bd体育手机客户端 名称:
ANTI-ACTIVIN RECEPTOR TYPE IA (ACVR1) (CENTER R147) antibody produced in rabbit
ACVR1
ACVRLK2
Activin receptor type-1
Activin receptor type I
Activin receptor-like kinase 2
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Activin A receptor type 1 (ACVR1) gene encodes a transmembrane protein that belongs to the bone morphogenetic protein (BMP) type I receptors subfamily of the transforming growth factor-β (TGF-β) receptors. ACVR1 is a single-pass type I membrane protein with a ligand-binding extracellular domain, a transmembrane domain, and a cytoplasmic domain. ACVR1 gene is expressed abundantly in endothelial cells, parenchymal cells, fibroblasts, and tumor-derived epithelial cells. This gene is located on human chromosome 2q24.1.

应用

Anti-Activin receptor type IA (ACVR1) (CENTER R147) antibody produced in rabbit has been used in immunohistochemistry (1:100) and western blot (1:100).

生化/生理作用

Activin A receptor type 1 (ACVR1) protein can bind activin in concert with activin receptor type 2 (ActRII) or activin receptor type-2B (ActRIIB). It participates in activin signaling. It is also capable of forming a complex with either the bone morphogenetic protein (BMP)-2/7-bound bone morphogenetic protein receptor type II (BMPR-II) or activin A receptor type 2A/2B (ACVR2A/ACVR2B). Somatic mutations of the ACVR1 gene are associated with primary ovary and colon cancer. It is considered a target gene to fibrodysplasia ossificans progressiva (FOP).

外形

Supplied in PBS with 0.09% (W/V) sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 IgG fraction of antiserum
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 57153 Da
species reactivity human, mouse
technique(s) immunohistochemistry: 1:50-1:100
western blot: 1:1000
NCBI登记号 NP_001096.1
UniProt登记号 Q04771
运输 wet ice
储存温度 ?20℃
Gene Information human ... ACVR1(90)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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