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位置: 首页> 品牌> Sigma-Aldrich> Anti-YB-1 (C-terminal) antibody produced in rabbit

Anti-YB-1 (C-terminal) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
Y0396
规格纯度
~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution
价格
5479.44 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-YB-1 (C-terminal) antibody produced in rabbit
Anti-BP-8
Anti-Y BOX binding protein
Anti-CSDB
Anti-CSDA2
Anti-MDR-NF1
Anti-DBPB
Anti-NSEP1
Anti-YBOX1
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Y-box-binding protein (YB-1) also known as nuclease-sensitive element-binding protein 1 (NSEP1) is a member of the Cold-Sock Domain (CSD) containing proteins. It is composed of three domains: the N-terminal which is thought to function as a trans-activation regulatory domain, a highly conserved nucleic acid binding domain (the CSD), and C-terminal domain, involved in protein-protein interactions.

特异性

Anti-YB-1 (C-terminal) antibody is specific for YB-1 in rats, mice and humans. The immunizing peptide specifically inhibits the detection of the YB-1 band by immunoblotting.

免疫原

synthetic peptide corresponding to amino acids 307-324 of human YB-1, conjugated to KLH. The corresponding sequence is identical in rat and mouse YB-1 proteins.

应用

Anti-YB-1 (C-terminal) antibody has been used in

  • immunoblotting
  • immunoprecipitation
  • immunofluorescence
  • double-immunostaining

生化/生理作用

Y-box-binding protein (YB-1) is shown to bind to the Y-box promoter element to regulate gene expression. It plays an important role in a wide variety of cellular functions such as transcriptional and translation regulation, DNA repair, drug resistance, and stress responses.

外形

Solution in 0.01 M phophate buffered saline, pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 200
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen ~50 kDa
species reactivity rat, mouse, human
浓度 ~1.0 mg/mL
technique(s) immunoprecipitation (IP): 5-10 μg using HEK-293T cell lysates
indirect immunofluorescence: 2-5 μg/mL using paraformaldehyde-fixed NIH-3T3 cells
western blot: 0.5-1 μg/mL using PC12 cell lysates
UniProt登记号 P67809
运输 dry ice
储存温度 ?20℃
Gene Information human ... YBX1(4904)
mouse ... Ybx1(22608)
rat ... Ybx1(500538)

安全信息

储存分类代码 12 - Non Combustible Liquids
个人防护装备 Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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