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Anti-SIRT1 antibody produced in rabbit

品牌
Sigma-Aldrich
货号
AV32386
规格纯度
affinity isolated antibody
价格
6305.78 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-SIRT1 antibody produced in rabbit
Anti-Sirtuin (silent mating type information Regulation 2 homolog) 1 ( S. cerevisiae)
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Sirtuin (silent mating type information regulation 2 homolog) 1(S. cerevisiae)(SIRT1), a member of the NAD(+)-dependent protein deacetylase SIRT family, is involved in the regulation of nuclear transcription of genes involve in energy metabolism. SIRT1 provides a link between cellular energy status sensing (NAD(+)status) and the regulation of energy homoeostasis. SIRT1 is involved in the regulation of metabolism, cell differentiation and senescence, stress response, and cancer.
Rabbit polyclonal anti-SIRT1 antibody reacts with chicken, human, mouse, rat, canine, and pig sirtuin-1 enzymes.

免疫原

Synthetic peptide directed towards the N terminal region of human SIRT1

应用

Rabbit polyclonal anti-SIRT1 antibody is used to tag sirtuin-1 for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of sirtuin-1 in NAD(+)status-dependent energy homeostasis at the level of nuclear transcription control and protein deacetylation.
Rabbit Anti-SIRT1 antibody can be used for western blot applications at a concentration of 0.5μg/ml.

生化/生理作用

SIRT1 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined;

序列

Synthetic peptide located within the following region: PETIPPPELDDMTLWQIVINILSEPPKRKKRKDINTIEDAVKLLQECKKI

外形

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 82 kDa
species reactivity rat, dog, guinea pig, rabbit, horse, bovine, mouse, human
浓度 0.5 mg - 1 mg/mL
technique(s) western blot: suitable
NCBI登记号 NP_036370
UniProt登记号 Q96EB6
运输 wet ice
储存温度 ?20℃
Gene Information human ... SIRT1(23411)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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