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Anti-CRMP2 antibody produced in rabbit

Anti-CRMP2 兔抗

品牌
Sigma-Aldrich
货号
C2993
规格纯度
~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution
价格
6366.52 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-CRMP2 antibody produced in rabbit
Anti-Collapsin Response Mediator Protein 2
Anti-Dihydropyriminidase Related Protein-2 (DRP2, DRP-2, DHPRP2)
Anti-Dihydropyriminidase-like 2 (DPYSL2)
Anti-TOAD-64
Anti-CRMP2 兔抗
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Collapsin response mediator proteins CRMPs) consist of a family of cytosolic phosphoproteins expressed in the nervous system and involved in neuronal differentiation and axonal guidance.

应用

Anti-CRMP2 antibody produced in rabbit has been used in:

  • western blotting
  • immunohistofluorescence
  • epifluorescence imaging
  • coimmunoprecipitation

生化/生理作用

CRMPs are a part of the collapsin/semaphorin signal transduction pathway implicated in semaphorin-induced growth cone collapse during neural development. CRMP2 is upregulated during development, and appears to be crucial for axon outgrowth. Glycogen synthase kinase 3 beta (GSK-3b) phosphorylates and inactivates CRMP-2 downstream of the phosphoinositide-3-kinase (PI3K/Akt) pathway, thus regulating neuronal polarity. CRMP2 interacts with tubulin dimers, kinesin-1 and WASP-family verprolin homologous protein 1 (WAVE1) complex to regulate axon outgrowth.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD03456049
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 200
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen ~62 kDa
species reactivity rat, human, mouse
增强验证 recombinant expression
Learn more aboutAntibody Enhanced Validation
浓度 ~1.0 mg/mL
technique(s) western blot: 0.1-0.2 μg/mL using HeLa whole cell lysate and mouse brain extract (S1 fraction)
UniProt登记号 Q16555
运输 dry ice
储存温度 ?20℃
Gene Information human ... DPYSL2(1808)
mouse ... Dpysl2(12934)
rat ... Dpysl2(25416)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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