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Anti-ALIX antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB4200476
规格纯度
~1.0 mg/mL, affinity isolated antibody
价格
5045.46 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-ALIX antibody produced in rabbit
Anti-dopamine receptor interacting protein 4
Anti-HP95
Anti-ALG-2 interacting protein 1
Anti-DRIP4
Anti-PDCD6IP
Anti-apoptosis-linked gene 2-interacting protein X
Anti-AIP1
Anti-programmed cell death 6 interacting protein
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

The gene PDCD6IP (programmed cell death 6 interacting protein), also known as ALIX (apoptosis-linked gene 2-interacting protein X), is mapped to human chromosome 3p22.1 The protein has a crescent-shaped Bro1 domain, V-shaped V domain and a proline-rich region.

免疫原

peptide corresponding to an internal region of human ALIX/ PDCD6IP, conjugated to KLH. The corresponding sequence is identical in monkey, bovine and dog and differs by 2 amino acids in mouse and rat.

应用

Anti-ALIX antibody produced in rabbit has been used in immunoprecipitation and immunoblotting.

生化/生理作用

ALIX (Apoptosis-linked gene 2 (ALG-2)-interacting protein X binds to endophilins, proteins that regulate membrane shape during endocytosis. Over-expression of ALIX and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death.
PDCD6IP (programmed cell death 6 interacting protein) interacts with PDCD6, a protein involved in apoptosis. It also participates in intraluminal endosomal vesicle biogenesis, viral budding and cytokinetic abscission. PDCD6IP is a part of the ESCRT (endosomal sorting complexes required for transport) machinery.

外形

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 200
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen ~95 kDa
species reactivity human, mouse
浓度 ~1.0 mg/mL
technique(s) immunoprecipitation (IP): 5-10 μg using lysates of human Jurkat cells.
western blot: 2.5-5 μg/mL using whole extracts of mouse A20 cells.
UniProt登记号 Q8WUM4
运输 dry ice
储存温度 ?20℃
Gene Information human ... PDCD6IP(10015)
mouse ... Pdcd6ip(18571)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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