半岛bd体育手机客户端 说明
一般描述
IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor, leading to the activation of MAP kinases and NF-kappaB. IL-33 induces production of helper T-cell type 2 (TH2) cytokines, including IL-4, IL-5 and IL-13, and is a known mediator of many inflammation responses. Cat. No. ABF108, Anti-IL-33, is an affinity purified rabbit polyclonal antibody that recognizes epitopes in the C-terminal half of murine IL-33. Reactivity to rat or other species has not been tested.
免疫原
Epitope: C-Terminal
His-tagged recombinant protein corresponding to the C-Terminal of mouse IL-33.
应用
Anti-IL-33 Antibody is an antibody against IL-33 for use in Western Blotting, Flow Cytometry.
Flow Cytometry Analysis: 0.25 ?g of this antibody from a representative lot detected IL-33 in 1X10E6 monensin treated MEF1 cells.
Research Sub Category
Immunoglobulins & Immunology
Research Category
Inflammation & Immunology
质量
Evaluated by Western Blotting in MEF1 cell lysate.
Western Blotting Analysis: 0.1 ?g/mL of this antibody detected IL-33 in 10 ?g of MEF1 cell lysate.
目标描述
~35 kDa observed. Uncharacterized band(s) may appear in some lysates.
外形
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to lot specific datasheet.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | affinity isolated antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
纯化方式 | affinity chromatography |
species reactivity | mouse |
technique(s) | flow cytometry: suitable western blot: suitable |
NCBI登记号 | NP_598536 |
UniProt登记号 | Q8BVZ5 |
运输 | wet ice |
安全信息
储存分类代码 | 12 - Non Combustible Liquids |
WGK | WGK 1 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich