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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-SIX2 antibody produced in mouse

Monoclonal Anti-SIX2 antibody produced in mouse

品牌
Sigma-Aldrich
货号
SAB1401533
规格纯度
clone 1G11, purified immunoglobulin, buffered aqueous solution
价格
5045.46 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Monoclonal Anti-SIX2 antibody produced in mouse
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila ′sine oculis′ homeobox protein. The encoded protein is a transcription factor which, like other members of this gene family, may be involved in limb or eye development. (provided by RefSeq)

免疫原

SIX2 (AAH24033, 1 a.a. ~ 291 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
MSMLPTFGFTQEQVACVCEVLQQGGNIERLGRFLWSLPACEHLHKNESVLKAKAVVAFHRGNFRELYKILESHQFSPHNHAKLQQLWLKAHYIEAEKLRGRPLGAVGKYRVRRKFPLPRSIWDGEETSYCFKEKSRSVLREWYAHNPYPSPREKRELTEATGLTTTQVSNWFKNRRQRDRAAEAKERENNENSNSNSHNPLNGSGKSVLGSSEDEKTPSGTPDHSSSSPALLLSPPPPGLPSLHSLGHPPGPSAVPVPVPGGGGADPLQHHHGLQDSILNPMSANLVDLGS

生化/生理作用

SIX2 (SIX homeobox 2) is responsible for the regulation of cartilage growth and differentiation in endochondral skeleton. SIX2 also participates in the craniofacial skeletal muscle formation. It might prevent the abnormal drooping eyelids, by weakening the ability of levator muscle to contract. SIX2 haploinsufficiency is linked with congenital ossicle malformation. Mutation in SIX2 is found to be associated with the development of urinary tract, kidney, anterior cranial base, limb tendon and the formation of pyloric sphincter. Deletion in the gene might cause autosomal dominant frontonasal dysplasia syndrome. Mutation in the gene leads to renal hypodysplasia and also chemotherapy-resistant blastemas.

外形

Solution in phosphate buffered saline, pH 7.4

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

质量水平 100
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 1G11, monoclonal
形式 buffered aqueous solution
species reactivity human
technique(s) capture ELISA: suitable
western blot: 1-5 μg/mL
同位素/亚型 IgG1κ
NCBI登记号 BC024033
UniProt登记号 Q9NPC8
运输 dry ice
储存温度 ?20℃
Gene Information human ... SIX2(10736)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable

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