半岛bd体育手机客户端 说明
一般描述
PUMA is one of the pro-apoptotic Bcl-2 family members including Bax and Noxa, which are also transcriptional targets of p53. The PUMA gene encodes two BH3 domain-containing proteins termed PUMA-a and PUMA-b. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis
特异性
Other species have not been tested.
The antibody reacts with the 21 kDa Puma BH3 domain protein.
免疫原
This antibody was developed against a synthetic peptide selected from the C-terminal region of human Puma.
应用
Anti-Puma BH3 domain Antibody is an antibody against Puma BH3 domain for use in WB.
质量
Western Blot Analysis: 1:250 dilution of this antibody detected Puma BH3 domain on mouse brain lysate.
目标描述
21 kDa
外形
Protein G Purified
Format: Purified
分析说明
Control
Western Blot : Mouse brain lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
eCl@ss | 32160702 |
NACRES | NA.41 |
半岛bd体育手机客户端 性质
生物来源 | rabbit |
质量水平 | 100 |
抗体形式 | purified antibody |
antibody product type | primary antibodies |
克隆 | polyclonal |
species reactivity | mouse |
technique(s) | western blot: suitable |
NCBI登记号 | NP_055232 |
UniProt登记号 | Q9BXH1 |
运输 | wet ice |
安全信息
储存分类代码 | 10 - Combustible liquids |
WGK | WGK 2 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich