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Anti-ATP7A antibody produced in chicken

品牌
Sigma-Aldrich
货号
GW21023
规格纯度
affinity isolated antibody, buffered aqueous solution
价格
4731.57 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-ATP7A antibody produced in chicken
Anti-Copper-transporting ATPase 1
Anti-Menkes disease-associated protein
Anti-ATPase, Cu++ transporting, α polypeptide
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

免疫原

Recombinant ATPase
Immunogen Sequence: GI # 4502321, sequence 1407-1500

应用

Anti-ATP7A antibody produced in chicken is suitable for western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

生化/生理作用

Copper-transporting ATPase 1 is a protein encoded by the ATP7A gene in humans. It mediates systemic copper absorption and provides cupro-enzymes in the trans-Golgi network (TGN) with copper. It constitutively cycles between the TGN and plasma membrane (PM) for regulating the metal homeostasis. Mutation in this gene causes Menkes disease, a rare X-linked recessive disorder characterized by multi-systemic disorder of copper deficiency. This disease is caused due to a novel "silent" substitution in the ATP7A gene.

外形

Solution in phosphate buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD03455449
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 chicken
质量水平 200
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity rat, human, mouse
manufacturer/tradename Genway 15-288-21023
technique(s) western blot: suitable
NCBI登记号 NP_000043.1
UniProt登记号 Q04656
运输 wet ice
储存温度 ?20℃
Gene Information human ... ATP7A(538)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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