您好,欢迎来到半岛电竞官方网址 ! [ 登录] [ 免费注册]
半岛电竞官方网址
位置: 首页> 品牌> Sigma-Aldrich> Anti-Synaptopodin (SE-19) antibody produced in rabbit

Anti-Synaptopodin (SE-19) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
S9442
规格纯度
IgG fraction of antiserum, buffered aqueous solution
价格
4731.57 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
Anti-Synaptopodin (SE-19) antibody produced in rabbit
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Synaptopodin is a proline-rich, actin-associated protein (100 kDa) is present in the post-synaptic density (PSD) in actin cytoskeleton. It is also present in the dendritic spines and differentiated podocytes. Synaptopodin contains a high amount of proline residues (~20%), which are evenly distributed along the protein sequence, thus virtually excluding the formation of globular domains. In particular, synaptopodin does not contain functional domains found in receptor clustering PSD proteins. Sequence comparison between human and mouse synaptopodin shows 84% identity. The exclusive site of synaptopodin expression in the telencephalon is restricted to specific areas of high synaptic plasticity, i.e. in the perykaria of the olfactory bulb, striatum, and hippocampus.

免疫原

synthetic peptide corresponding to amino acids 184-202 of rat synaptopodin conjugated to KLH. This rat synaptopodin sequence has ~70% identity with human synaptopodin.

应用

Anti-Synaptopodin (SE-19) antibody produced in rabbit has been used in:

  • immunofluorescence microscopy
  • immunohistochemistry
  • western blotting

生化/生理作用

Synaptopodin is thought to play an important role in synaptic plasticity and is associated in the modulation of motility of actin in neuronal dendritic spines. The association of synaptopodin with the specialized actin system of renal podocyte foot processes suggests that it may play a role in actin cytoskeleton dynamics of these cellular extensions. Synaptopodin has been found to interact with α-actinin-4 and the tight junction protein Membrane-associated guanylate kinase inverted 1 (MAGI-1) in Madin-Darby Canine Kidney (MDCK) cells.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD05865391
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 200
偶联物 unconjugated
抗体形式 IgG fraction of antiserum
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen 100 kDa
species reactivity rat
technique(s) microarray: suitable
western blot: 1:3,000 using cytosolic S1 fraction of rat brain
UniProt登记号 Q9Z327
运输 dry ice
储存温度 ?20℃
Gene Information human ... SYNPO(11346)
rat ... Synpo(60324)

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H302 - H412
预防措施声明 P273 - P301 + P312 + P330
危险分类 Acute Tox. 4 Oral - Aquatic Chronic 3
储存分类代码 12 - Non Combustible Liquids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

Sigma-Aldrich

推荐半岛bd体育手机客户端
Baidu
map