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Anti-PCNA antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB2701819
规格纯度
affinity isolated antibody, buffered aqueous solution
价格
4618.16 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-PCNA antibody produced in rabbit
PCNA
wu:fa28e03
fb36g03
cb16
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Proliferating cell nuclear antigen (PCNA) is a ring-shaped homotrimer protein, that is located at the center of the faithful duplication of eukaryotic genomes. Since it encircles the DNA, PCNA is also known as a sliding clamp. This gene is mapped to human chromosome 20p12.3.

免疫原

Recombinant protein containing a sequence corresponding to a region within amino acids 31 and 222 of pcna according to NP_571479

应用

Suggested starting dilutions are as follows: IHC-P: 1:100-1:1000, WB: 1:500-1:3000, IHC-Wm: 1:50-1:500, Immunostaining: Assay-dependent dilution. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.
Anti-PCNA antibody has been used in the detection of proliferating cells by immunofluorescence.

生化/生理作用

This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase′s processibility during elongation of the leading strand.
Proliferating cell nuclear antigen (PCNA) controls the production of the leading and lagging strands, which are required for the duplication of DNA. It acts as a cell cycle regulatory protein. This protein regulates apoptosis. PCNA is also involved in non-replicative DNA synthesis events.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

1XPBS, 1% BSA, 20% Glycerol (pH7). 0.025% ProClin 300 was added as a preservative.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity zebrafish, (Japanese Medaka)
technique(s) immunohistochemistry: suitable
western blot: 500-3000
NCBI登记号 NP_571479
运输 wet ice
储存温度 ?20℃
Gene Information zebrafish ... pcna(30678)

安全信息

象形图 GHS07
警示用语: Warning
危险声明 H317 - H412
预防措施声明 P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
危险分类 Aquatic Chronic 3 - Skin Sens. 1
储存分类代码 12 - Non Combustible Liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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