Anti-Histone lysine demethylase NO66 Antibody

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一般描述

NO66 is a lysine-specific demethylase that removes methyl groups from histone H3 at lysine 4 and lysine 36. This enzyme has been shown to more readily demethylate trimethylated H3 ′Lys-4′ (H3K4me3) and monomethylated H3 Lys4 (H3K4me1) consistent with its role in modulating the histone code. This protein is a highly conserved, constitutive nucleolar component that shows a dual localization pattern with strong enrichment in the granular part of nucleoli and in distinct nucleoplasmic entities.

特异性

This antibody recognizes Histone lysine demethylase NO66 near the N-terminus.

免疫原

Epitope: Near N-terminus
KLH-conjugated linear peptide corresponding to human Histone lysine demethylase NO66 near the N-terminus.

应用

Research Category
Epigenetics & Nuclear Function
Research Sub Category
Chromatin Biology
Detect NO66 using this rabbit polyclonal antibody, Anti-Histone lysine demethylase NO66 Antibody validated for use in western blotting.

质量

Evaluated by Western Blotting in A431 cell lysate.

Western Blotting Analysis: 2.0 ?g/mL of this antibody detected Histone lysine demethylase NO66 in 10 ?g of A431 cell lysate.

目标描述

~66 kDa observed

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
A431 cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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