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位置: 首页> 品牌> Sigma-Aldrich> Monoclonal Anti-POU5F1 (Oct4) antibody produced in mouse

Monoclonal Anti-POU5F1 (Oct4) antibody produced in mouse

品牌
Sigma-Aldrich
货号
P0082
规格纯度
~1.0 mg/mL, clone PF-29, purified immunoglobulin, buffered aqueous solution
价格
5241.99 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Monoclonal Anti-POU5F1 (Oct4) antibody produced in mouse
Anti-OTF3
Anti-POU domain, class 5, transcription factor 1
Anti-OCT4
Anti-OCT3
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

POU5F1 (POU class 5 homeobox 1) gene codes for a transcription factor that binds to octamer sequence. POU5F1 is mapped to human chromosome 6p21.33.
Monoclonal Anti-POU5F1 (Oct4) (mouse IgG2a isotype) is derived from the hybridoma PF-29 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice, immunized with a peptide.

特异性

Monoclonal Anti-POU5F1 (Oct4) recognizes human POU5F1/Oct4.

免疫原

amino acids 20-37 of human POU5F1 peptide.

应用

Monoclonal Anti-POU5F1 (Oct4) antibody produced in mouse may be used in:

  • immunoblotting
  • immunocytochemistry
  • enzyme-linked immunosorbent assay (ELISA)

生化/生理作用

POU5F1 protein functions as an early developmental control gene. This protein has been recognized as fundamental in the maintenance of pluripotency of embryonic stem cells and primordial germ cells. POU5F1 protein has been proposed as a useful marker for germ cell tumors (GCTs) that can exhibit pluripotential, specifically seminoma/ dysgerminoma/germinoma and embryonal carcinoma (EC). POU5F1 has also been established as a marker for extragonadal germ cell tumors (GCT) and metastatic tumors.
POU5F1 (POU class 5 homeobox 1) controls homeostasis of embryonic cell development and pluripotency. The POU5F1 gene is highly expressed in cancer cells and offers resistance against chemotherapy.

外形

0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。

储存及稳定性

For continuous use, store at 2-8 ℃ for up to one month. For extended storage, freeze at -20 ℃ in working aliquots. Repeated freezing and thawing, or storage in “frost-free” freezers, is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

半岛bd体育手机客户端 性质

质量水平 200
生物来源 mouse
偶联物 unconjugated
抗体形式 purified immunoglobulin
antibody product type primary antibodies
克隆 PF-29, monoclonal
形式 buffered aqueous solution
分子量 antigen ~43 kDa
species reactivity human
浓度 ~1.0 mg/mL
technique(s) immunocytochemistry: suitable
indirect ELISA: suitable
western blot: 0.5-1 μg/mL using NT2/D1 total cell extract
UniProt登记号 Q01860
运输 dry ice
储存温度 ?20℃
Gene Information human ... POU5F1(5460)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)

Sigma-Aldrich

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