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位置: 首页> 品牌> Sigma-Aldrich> Anti-MEIOB Antibody

Anti-MEIOB Antibody

品牌
Sigma-Aldrich
货号
ABE1414
规格纯度
serum, from rabbit
价格
4848.93 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-MEIOB Antibody
Meiosis-specific with OB domain-containing protein, Protein expressed in male leptotene and zygotene spermatocytes 675, MLZ-675
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

MEIOB is a single stranded binding protein required for proper homologous recombination in meiosis I. MEIOB is required for proper DNA strand repair at double strand breaks and faithful synapsis of the chromosomes. MEIOB is also required for successful completion of meiotic recombination and is part of a multiprotein complex with RPA2 and SPATA22 proteins. MEIOB is expressed in the gonads and specifically in ovary and testis starting at the 14th weeks post fertilization. MEIOB is also expressed in a variety of tumors but not in other tissues other than testis and ovary. Because of its unique expression MEIOB is being examined as a possible anti-cancer autoimmune agent.

免疫原

Recombinant protein corresponding to mouse MEIOB.

应用

Research Sub Category
Nuclear Receptors
Research Category
Epigenetics & Nuclear Function
Immunoprecipitation Analysis: A representative lot immunoprecipitated MEIOB in P18 testes (Luo, M., et al. (2013). Nature. DOI: 10.1038/ncomms3788 pg. 1-12).
Immunocytochemistry Analysis: A representative lot detected MEIOB in mouse spermatocytes (Luo, M., et al. (2013). Nature. DOI: 10.1038/ncomms3788 pg. 1-12).
This Anti-MEIOB Antibody is validated for use in Western Blotting and Immunoprecipitation and Immunocytochemistry for the detection of MEIOB.

质量

Evaluated by Western Blotting in mouse testis tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected MEIOB in 10 ?g of mouse testis tissue lysate.

目标描述

~50 kDa observed. Uncharacterized band(s) may appear in some lysates.

外形

Rabbit polyclonal serum with 0.05% sodium azide.
Unpurified

储存及稳定性

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

其他说明

Concentration: Please refer to lot specific datasheet.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 serum
antibody product type primary antibodies
克隆 polyclonal
species reactivity mouse
technique(s) immunocytochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
NCBI登记号 NP_083473
UniProt登记号 Q9D513
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 2
闪点(F) Not applicable
闪点(C) Not applicable

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