Anti-SARM Antibody

半岛bd体育手机客户端 说明

一般描述

Sterile alpha and Armadillo repeat protein (SARM), also known as Sterile alpha and TIR motif-containing protein 1 (SARM1) and Sterile alpha motif domain-containing protein 2 (SAMD2), is involved in the innate immnune response. SARM blocks TICAM1/TRIF-dependent transcription-factor activation and gene induction, without affecting the MYD88-dependent pathway or non-TLR signaling. SARM is expressed kidney and liver with lower levels found in placenta.

特异性

This antibody recognizes the C-terminus of SARM.

免疫原

KLH-conjugated linear peptide corresponding to the C-terminus of human SARM.
Epitope: C-terminus

应用

Immunocytochemistry Analysis: 2 ?g/mL from a representative lot detected SARM in Daudi cells.

Immunofluorescence Analysis: 2 ?g/mL from a representative lot detected SARM in Daudi cells.
Detect Sterile alpha & Armadillo repeat protein using this rabbit polyclonal antibody, Anti-SARM Antibody validated for use in western blotting, ICC & Immunofluorescence.
Research Sub Category
Immunoglobulins & Immunology
Research Category
Inflammation & Immunology

质量

Evaluated by Western Blotting in Daudi cell lysate.

Western Blotting Analysis: 1 ?g/mL of this antibody detected SARM in 15 ?g of Daudi cell lysate.

目标描述

~89 kDa observed. Uncharacterized bands may appear in some lysates.

外形

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
Antigen Affinity Purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Daudi cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
纯化方式	affinity chromatography
species reactivity	human
technique(s)	immunocytochemistry: suitable immunofluorescence: suitable western blot: suitable
UniProt登记号	Q6SZW1
运输	wet ice
Gene Information	human ... SARM1(23098)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 2
闪点(F)	Not applicable
闪点(C)	Not applicable