半岛bd体育手机客户端 说明
一般描述
Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.
免疫原
KLH-conjugated linear peptide corresponding to human FEZ2.
应用
Research Sub Category
Developmental Neuroscience
Neuroregenerative Medicine
Research Category
Neuroscience
Neuroscience
Detect the FEZ2 protein using this Anti-FEZ2 validated for use in WB & IF.
Immunofluorescence Analysis: 5 ?g/mLfrom a representative lot detected FEZ2 in human brain tissue.
质量
Evaluated by Western Blot in 3T3 cell lysate.
Western Blot Analysis: 1 ?g/mL of this antibody detected FEZ2 in 15 ?g of 3T3 cell lysate.
目标描述
~38/50 kDa observed. An uncharacterized band may appear at ~48 kDa in some lysates.
外形
Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide.
Antigen Affinity Purified
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
3T3 cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| eCl@ss | 32160702 |
| NACRES | NA.41 |
半岛bd体育手机客户端 性质
| 生物来源 | rabbit |
| 质量水平 | 100 |
| 抗体形式 | affinity isolated antibody |
| antibody product type | primary antibodies |
| 克隆 | polyclonal |
| 纯化方式 | affinity chromatography |
| species reactivity | human, mouse |
| technique(s) | immunofluorescence: suitable western blot: suitable |
| 同位素/亚型 | IgG |
| UniProt登记号 | Q9UHY8 |
| 运输 | wet ice |
| Gene Information | human ... FEZ2(9637) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 1 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
