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Anti-DYRK1A (N-terminal) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
D1694
规格纯度
~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution
价格
4731.57 *本价格含增值税费
促销
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数量
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半岛bd体育手机客户端 名称:
Anti-DYRK1A (N-terminal) antibody produced in rabbit
Anti-MBN/MNBH
Anti-Minibrain Drosophilahomolog
Anti-MNB protein kinase
Anti-Dual-specificity tyrosine-phosphorylation-regulated kinase 1A
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

DYRK1A (dual-specificity tyrosine-phosphorylated regulated kinase 1A) is a member of a growing family of Ser/Thr protein kinases termed DYRKs.
The human and rodent DYRK1A are ubiquitously expressed in adult and fetal tissue with high expression in the brain and heart during development.

应用

Anti-DYRK1A (N-terminal) antibody produced in rabbit has been used in immunoblotting and immunohistochemistry.

生化/生理作用

DYRK1A is encoded by a gene located within the Down syndrome (DS) critical region on human chromosome 21 and its expression is found to be elevated in individuals with DS. It might be one of the genes involved in some of the neurological abnormalities observed in DS. It phosphorylates several substrates including transcription factor FKHR, NFAT, STAT3, microtubule-associated protein Tau, glycogen synthase and c-AMP-response element-binding protein.

目标描述

DYRK1A (N-terminal) encodes a member of the Dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-c

外形

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 200
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
分子量 antigen ~86 kDa
species reactivity rat, mouse, human
浓度 ~1.5 mg/mL
technique(s) western blot: 1.5-3 μg/mL using rat brain embryonic extract (S1 fraction)
western blot: 3-5 μg/mL using PC12 cell lyste
UniProt登记号 Q13627
运输 dry ice
储存温度 ?20℃
Gene Information human ... DYRK1A(1859)
mouse ... Dyrk1a(13548)
rat ... Dyrk1a(25255)

安全信息

储存分类代码 12 - Non Combustible Liquids
闪点(F) Not applicable
闪点(C) Not applicable
个人防护装备 Eyeshields, Gloves

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