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位置:首页 > 品牌 > Sigma-Aldrich > ANTI-CD11B(N-TERMINAL) antibody produced in rabbit

ANTI-CD11B(N-TERMINAL) antibody produced in rabbit

品牌
Sigma-Aldrich
货号
SAB1305652
规格纯度
affinity isolated antibody, buffered aqueous solution
价格
6662.67 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
-+
半岛bd体育手机客户端 名称:
ANTI-CD11B(N-TERMINAL) antibody produced in rabbit
ITGAM
CD11 antigen-like family member B
Integrin alpha-M
CD11B
CR3A
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Cluster of differentiation 11b (CD11b), also known as integrin subunit α M (ITGAM), is encoded by the gene mapped to human chromosome 16p11.2. It belongs to the integrin α chain family. CD11b is expressed by a variety of myeloid cell types, such as dendritic cells, macrophages, monocytes and neutrophils.

生化/生理作用

Cluster of differentiation 11b (CD11b) acts as a receptor for complement component C3 degradation product, iC3b. CD11b interacts with β2 chain (ITGB2) to form a leukocyte integrin (MAC-1 or complement receptor 3 (CR3)), which in turn plays a crucial role in adherence of neutrophils and monocytes to stimulated endothelium. Mutation in the gene increases the risk of susceptibility to systemic lupus erythematosus (SLE) and acute inflammatory demyelinating polyradiculoneuropathy (AIDP).

外形

Supplied in PBS with 0.09% (W/V) sodium azide

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

NACRESNA.41

半岛bd体育手机客户端 性质

生物来源rabbit
质量水平100
抗体形式affinity isolated antibody
antibody product typeprimary antibodies
克隆polyclonal
形式buffered aqueous solution
分子量 127179 Da
species reactivityhuman
technique(s)flow cytometry: 1:10-1:50
immunohistochemistry: 1:50-1:100
western blot: 1:1000
NCBI登记号NP_000623.2
UniProt登记号P11215
运输wet ice
储存温度−20℃
Gene Informationhuman ... ITGAM(3684)

安全信息

储存分类代码12 - Non Combustible Liquids
闪点(F)Not applicable
闪点(C)Not applicable

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