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位置: 首页> 品牌> Sigma-Aldrich> Anti-Oxytocin receptor Antibody

Anti-Oxytocin receptor Antibody

品牌
Sigma-Aldrich
货号
ABN297
规格纯度
from rabbit, purified by affinity chromatography
价格
5688.25 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-Oxytocin receptor Antibody
Oxytocin receptor, OT-R
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Oxytocin is a cyclic 9 amino acid peptide that differs from vasopressin in 2 amino acids. Despite the close similarities in sequence, oxytocin and vasopressin have different biological activities and bind to distinct G protein-coupled receptors. The oxytocin receptor, OT, couples primarily to Gq/11 to mobilize intracellular calcium. In female reproduction, oxytocin promotes uterine contraction and lactation; oxytocin is the most commonly used drug for induction of labor, whereas an oxytocin antagonist, atosiban, is under investigation to suppress preterm labor. Oxytocin/OT interaction in the CNS also plays an important role in stress, male and female sexual response, and sociality.

免疫原

KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Oxytocin receptor.
Epitope: Cytoplasmic domain

应用

Anti-Oxytocin receptor Antibody is a highly specific rabbit polyclonal antibody, that targets Oxytocin Receptor & has been tested in western blotting.
Research Category
Neuroscience
Research Sub Category
Developmental Signaling

质量

Evaluated by Western Blotting in MCF7 cell lysate.

Western Blotting Analysis: 0.5 ?g/mL of this antibody detected Oxytocin receptor in 10 ?g of MCF7 cell lysate.

目标描述

~45/65 kDa observed The calculated molecular weight of this protein is 43 kDa However, this protein has been observed at ~60-70 kDa due to glycoslyatation (Zhong, M.m et al. (2012). Molecular Cancer Research. 1-25). Uncharacterized band(s) may appear in some lysates.

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity human, mouse
technique(s) western blot: suitable
NCBI登记号 NP_000907
UniProt登记号 P30559
运输 wet ice
Gene Information human ... OXTR(5021)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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