Anti-Olfactomedin-4/OLFM4 Antibody

半岛bd体育手机客户端 说明

一般描述

OLFM4, also known as Olfactomedin-4, Antiapoptotic protein GW112, G-CSF-stimulated clone 1 protein (hGC-1), or hOLfD, and encoded by the gene OLFM4/GW112 is a multimeric protein that has been found both extracellularly, interacting with cell surface lectins and cadherin proteins, and intracellularly within the mitochondria and cytoplasm. OLFM4 is expressed during myeloid lineage development but also in found in adult prostate, bone marrow, and stomach, as well as pancreatic cancer cells. The protein appears to govern cell proliferation in pancreatic cancer cells however in leukemic cell lines it inhibits cell growth and induces cell differentiation and apoptosis. The gene is induced by retinoic acid contact and signaling is linked via the NFkappaB pathway.

免疫原

KLH-conjugated linear peptide corresponding to the C-terminus of human Olfactomedin-4/OLFM4.
Epitope: C-terminus

应用

Research Sub Category
Apoptosis - Additional
Anti-Olfactomedin-4/OLFM4 Antibody is an antibody against Olfactomedin-4/OLFM4 for use in western blotting & IHC.
Western Blotting Analysis: 2.0 ?g/mL of this antibody detected Olfactomedin-4/OLFM4 in 10 ?g of human liver tissue lysate.
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Olfactomedin-4/OLFM4 in human pancreatic cancer sections and human prostate tissue.
Research Category
Apoptosis & Cancer

质量

Evaluated by Western Blotting in human small intestine tissue lysate.

Western Blotting Analysis: 2.0 ?g/mL of this antibody detected Olfactomedin-4/OLFM4 in 10 ?g of human small intestine tissue lysate.

目标描述

~64 kDa observed. The calculated molecular weight of this protein is 57 kDa, but can be observed at ~64 kDa due to high glycosylation.

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss	32160702
NACRES	NA.41

半岛bd体育手机客户端 性质

生物来源	rabbit
质量水平	100
抗体形式	affinity isolated antibody
antibody product type	primary antibodies
克隆	polyclonal
纯化方式	affinity chromatography
species reactivity	human
technique(s)	immunohistochemistry: suitable western blot: suitable
NCBI登记号	NP_006409
UniProt登记号	Q6UX06
运输	wet ice
Gene Information	human ... OLFM4(10562)

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable