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Anti-Follicle-Stimulating Hormone Receptor antibody produced in rabbit

品牌
Sigma-Aldrich
货号
F3929
规格纯度
affinity isolated antibody, buffered aqueous solution
价格
7219.49 *本价格含增值税费
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半岛bd体育手机客户端 名称:
Anti-Follicle-Stimulating Hormone Receptor antibody produced in rabbit
Anti-FSHR
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Follicle stimulating hormone receptor (FSHR) belongs to the G protein-coupled receptors family and is a glycoprotein. FSHR gene is mapped to human chromosome 2p16.3. FSHR comprises hydrophilic domain, hydrophobic membrane regions, C-terminal extracellular domain, and short intracellular domain.

免疫原

synthetic peptide coresponding to the N-terminal extracellular domain of human follicle-stimulating hormone receptor, conjugated to KLH. The immunizing peptide has 24% identity and 29% similarity with the mouse gene.

应用

Anti-Follicle-Stimulating Hormone Receptor antibody produced in rabbit has also been used in immunohistochemistry in ovine and reproductive tissues. It has also been used in western blotting.

生化/生理作用

Follicle stimulating hormone receptor (FSHR) is located on Sertoli cells of the testes and the granulosa cells of ovary. The pituitary glycoprotein hormone, FSH, binds to FSHR and regulates the function of gonads and overall fertility. In Sertoli cells, FSHR-mediated cell proliferation determines the spermatogenic output. In ovarian granulosa cells, FSHR signaling mediates follicular growth and maturation of oocytes. Polymorphisms in the FSHR is implicated in premature ovarian insufficiency.

外形

Solution in phosphate buffered saline containing 0.1% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号 MFCD00162296
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 200
偶联物 unconjugated
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
形式 buffered aqueous solution
species reactivity human
availability not available in Japan
technique(s) immunohistochemistry (formalin-fixed, paraffin-embedded sections): 7-14 μg/mL
UniProt登记号 P23945
运输 dry ice
储存温度 ?20℃
Gene Information human ... FSHR(2492)
mouse ... Fshr(14309)
rat ... Fshr(25449)

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK nwg
闪点(F) Not applicable
闪点(C) Not applicable

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