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位置: 首页> 品牌> Sigma-Aldrich> Anti-Dopamine D(1A) Receptor Antibody

Anti-Dopamine D(1A) Receptor Antibody

品牌
Sigma-Aldrich
货号
ABN20
规格纯度
from rabbit, purified by affinity chromatography
价格
7029.8 *本价格含增值税费
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数量
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半岛bd体育手机客户端 名称:
Anti-Dopamine D(1A) Receptor Antibody
dopamine receptor D1, D(1A) dopamine receptor
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

一般描述

Dopaminergic signals are thought to modulate corticostriatal synapses onto medium spiny projection neurons, and this plasticity is, in turn, thought to alter patterns of activity during learning. Subversion of these processes in clinical and rodent models is hypothesized to contribute importantly to addiction to psychostimulants, seizures, and movement disorders in Huntington’s (HD) and Parkinson’s disease (PD). Dopamine receptor D1, also known as DRD1, is the most abundant dopamine receptor (of the five types D1-D5) in the central nervous system and is critically involved in these processes and the modulation of D2 receptor mediated events. Coupled with G-protein, the D1a receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases including the key molecular switch, DARPP-32.

特异性

This antibody recognizes D(1A) dopamine receptor.

免疫原

KLH-conjugated linear peptide of rat dopamine D(1A) receptor at and around the cytoplasmic domain.
Epitope: Cytoplasmic Domain

应用

Immunohistochemistry Analysis: A 1:300 dilution from a previous lot detected D(1A) dopamine receptor in rat brain tissue.

ELISA Analysis: Tested in ELISA against antigen-coated plate. A 1:100 dilution from a previous lot detected dopamine D(1A) receptor peptide.
Research Category
Neuroscience
Anti-Dopamine D(1A) Receptor Antibody detects level of Dopamine D(1A) Receptor & has been published & validated for use in IH, WB, ELISA.
Research Sub Category
Neurotransmitters & Receptors

质量

Evaluated by Western Blot in rat testis tissue lysate.

Western Blot Analysis: 2 ?g/ml of this antibody detected dopamine D(1A) receptor in 10 ?g of rat testis tissue lysate.

目标描述

~ 55 kDa is observed

联系

Replaces: AB1765P;

外形

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide.
Affinity purified

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
Rat testis tissue lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

eCl@ss 32160702
NACRES NA.41

半岛bd体育手机客户端 性质

生物来源 rabbit
质量水平 100
抗体形式 affinity isolated antibody
antibody product type primary antibodies
克隆 polyclonal
纯化方式 affinity chromatography
species reactivity rat
species reactivity (predicted by homology) bovine (based on 100% sequence homology)
technique(s) ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
NCBI登记号 NP_036678
UniProt登记号 P18901
运输 wet ice

安全信息

储存分类代码 12 - Non Combustible Liquids
WGK WGK 1
闪点(F) Not applicable
闪点(C) Not applicable

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