Anti-LBR antibody produced in mouse

半岛bd体育手机客户端 说明

一般描述

Lamin B receptor (LBR) is a transmembrane protein which is expressed in the inner nuclear membrane. It possesses an amino-terminal domain, eight transmembrane domains and a carboxyl-terminal region. The gene encoding LBR is localized on human chromosome 1q42.

免疫原

LBR (NP_002287.2, 1 a.a. ~ 615 a.a) full-length human protein.

Sequence
MPSRKFADGEVVRGRWPGSSLYYEVEILSHDSTSQLYTVKYKDGTELELKENDIKPLTSFRQRKGGSTSSSPSRRRGSRSRSRSRSPGRPPKSARRSASASHQADIKEARREVEVKLTPLILKPFGNSISRYNGEPEHIERNDAPHKNTQEKFSLSQESSYIATQYSLRPRREEVKLKEIDSKEEKYVAKELAVRTFEVTPIRAKDLEFGGVPGVFLIMFGLPVFLFLLLLMCKQKDPSLLNFPPPLPALYELWETRVFGVYLLWFLIQVLFYLLPIGKVVEGTPLIDGRRLKYRLNGFYAFILTSAVIGTSLFQGVEFHYVYSHFLQFALAATVFCVVLSVYLYMRSLKAPRNDLSPASSGNAVYDFFIGRELNPRIGTFDLKYFCELRPGLIGWVVINLVMLLAEMKIQDRAVPSLAMILVNSFQLLYVVDALWNEEALLTTMDIIHDGFGFMLAFGDLVWVPFIYSFQAFYLVSHPNEVSWPMASLIIVLKLCGYVIFRGANSQKNAFRKNPSDPKLAHLKTIHTSTGKNLLVSGWWGFVRHPNYLGDLIMALAWSLPCGFNHILPYFYIIYFTMLLVHREARDEYHCKKKYGVAWEKYCQRVPYRIFPYIY

生化/生理作用

Lamin B receptor (LBR) inhibits immature chromatin binding of proteins. It has a role in the construction of the nuclear envelopein vitroandin vivo. Mutation in the gene encoding LBR has been linked to Pelger-Hu?t anomaly (PHA).

外形

Solution in phosphate buffered saline, pH 7.4

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

基本信息

MDL编号	MFCD01634008
NACRES	NA.41

半岛bd体育手机客户端 性质

质量水平	100
生物来源	mouse
偶联物	unconjugated
抗体形式	IgG fraction of antiserum
antibody product type	primary antibodies
克隆	polyclonal
形式	buffered aqueous solution
species reactivity	human
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable indirect immunofluorescence: suitable western blot: 1 μg/mL
UniProt登记号	Q14739
运输	dry ice
储存温度	?20℃
Gene Information	human ... LBR(3930)

安全信息

储存分类代码	12 - Non Combustible Liquids
闪点(F)	Not applicable
闪点(C)	Not applicable