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位置: 首页> 品牌> Sigma-Aldrich> 9-(2-脱氧-β- D -呋喃核糖基)鸟嘌呤

2′-Deoxyguanosine monohydrate

2'-脱氧鸟苷 一水合物

品牌
Sigma-Aldrich
CAS
312693-72-4
货号
D7145
规格纯度
99-100%
价格
520.95 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
312693-72-4
2′-Deoxyguanosine monohydrate
9-(2-Deoxy-β- D -ribofuranosyl)guanine
Guanine-2′-deoxyriboside
2'-脱氧鸟苷 一水合物
9-(2-脱氧-β- D -呋喃核糖基)鸟嘌呤
鸟嘌呤-2′-脱氧核苷
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

2′-Deoxyguanosine monohydrate has been used as a nucleoside supplement:

  • to study its effect on mitochondrial DNA copy number in deoxyguanosine kinase (dguok) mutant zebrafish,
  • in tissue culture medium for deoxyribonucleotide triphosphate (dNTP) synthesis,
  • in RPMI (Roswell Park Memorial Institute)-1640 medium to eliminate the endogenous thymocytes

包装

1, 5 g in poly bottle
25, 100 mg in poly bottle

生化/生理作用

Deoxyguanosine (dG) is a purine nucleoside that upon sequential phosphorylation (kinases) forms deoxyguanosine triphosphate (dGTP) which is used by DNA polymerases and reverse transcriptases to synthesize DNA(s). Deoxyguanosine is the most electron-rich of the four canonical bases and includes many nucleophilic sites which are susceptible to oxidative damage. This makes deoxyguanosine and its oxidized derivatives useful reagents to study mechanisms of oxidative damage to nucleosides and nucleotides.

基本信息

经验(实验)分子式 C10H13N5O4· H2O
分子量 285.26
Beilstein 39814
MDL编号 MFCD00150760
PubChem化学物质编号 24894083
NACRES NA.51

半岛bd体育手机客户端 性质

质量水平 200
生物来源 synthetic (organic)
测定 99-100%
形式 powder
溶解性 1 M NH4OH: 50 mg/mL, clear, colorless
SMILES string O.NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](CO)O3)C(=O)N1
InChI 1S/C10H13N5O4.H2O/c11-10-13-8-7(9(18)14-10)12-3-15(8)6-1-4(17)5(2-16)19-6;/h3-6,16-17H,1-2H2,(H3,11,13,14,18);1H2/t4-,5+,6+;/m0./s1
InChI key LZSCQUCOIRGCEJ-FPKZOZHISA-N

安全信息

储存分类代码 13 - Non Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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