尼索地平 - 半岛电竞官方网址

尼索地平

品牌

Sigma-Aldrich

CAS

63675-72-9

货号

N0165

包装型号

规格纯度

≥98% (HPLC)

价格

846.6 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

63675-72-9
Nisoldipine
(±)-Isobutyl methyl 1,4-dihydro-2,6-dimethyl-4-( o-nitrophenyl)-3,5-pyridinedicarboxylate
1,4-Dihydro-2,6-dimethyl-4-(2-nitrophenyl)-3,5-pyridinedicarboxylic acid methyl 2-methylpropyl ester
Sular
尼索地平

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

应用

Nisoldipine has been used:

as a hit-antagonist to study its effects on oxytocin (OT)-induced myometrial Ca²⁺-mobilization and its potency to dampen uterine myometrial contractions
as a calcium channel blocker to study its effects on cell viability in a human hepatic cancer HepG2 and rat renal epithelial NRK52E cell line
as a component of the external IK1 recording solution to study the action potential in human pluripotent stem cell?derived cardiomyocytes (hiPS-CMs)

包装

10, 50 mg in glass bottle

生化/生理作用

L-type (CaV1.2) calcium channel blocker; dihydropyridine-type calcium channel blocker with selectivity for smooth muscle (CaV1.2b) over cardiac muscle (CaV1.2a). Arterial vasodilator and antihypertensive agent.

特点和优势

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Bayer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. N0165.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

基本信息

经验(实验)分子式	C₂₀H₂₄N₂O₆
分子量	388.41
EC 号	264-407-7
MDL编号	MFCD00478055
PubChem化学物质编号	329818405
NACRES	NA.77

半岛bd体育手机客户端性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	yellow
溶解性	DMSO: >10 mg/mL
创始人	Bayer
储存温度	room temp
SMILES string	COC(=O)C1=C(C)NC(C)=C(C1c2ccccc2[N+]([O-])=O)C(=O)OCC(C)C
InChI	1S/C20H24N2O6/c1-11(2)10-28-20(24)17-13(4)21-12(3)16(19(23)27-5)18(17)14-8-6-7-9-15(14)22(25)26/h6-9,11,18,21H,10H2,1-5H3
InChI key	VKQFCGNPDRICFG-UHFFFAOYSA-N
Gene Information	human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779)

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 1
闪点(F)	Not applicable
闪点(C)	Not applicable