Lyso SM (d18:1)

半岛bd体育手机客户端 说明

一般描述

Lyso SM (d18:1), also known as sphingosylphosphorylcholine (SPC), is a bioactive lipid molecule. This lysophospholipid is present in normal blood plasma, ascites and various tissues.

应用

Lyso SM (d18:1) has been used:

• to study its effect on the skeletal muscle ryanodine receptor (RyR1), in the presence and absence of calmodulin through single channel recordings in planar lipid bilayers
• as an inhibitor of Ca²⁺sensor calmodulin (CaM)
• as a standard in circular dichroism (CD) spectroscopy to determine lipid selectivity of the lipid-peptide interactions

生化/生理作用

Lyso SM (d18:1) or sphingosylphosphorylcholine (SPC) is a lipid mediator that exhibits second messenger functions. It regulates ryanodine receptors (RyRs) and releases Ca²⁺from the sarco/endoplasmic reticulum. Lyso SM (d18:1) acts as an endogenous inhibitor of ubiquitous Ca²⁺sensor calmodulin (CaM).

包装

5 mL Amber Glass Screw Cap Vial (860600P-25mg)
5 mL Amber Glass Screw Cap Vial (860600P-50mg)
5 mL Amber Glass Screw Cap Vial (860600P-5mg)
5 mL Amber Glass Screw Cap Vial (860600P-10mg)

基本信息

经验(实验)分子式	C23H49N2O5P
分子量	464.62
NACRES	NA.25

半岛bd体育手机客户端 性质

形式	powder
包装	pkg of 1 × 10 mg (860600P-10mg) pkg of 1 × 25 mg (860600P-25mg) pkg of 1 × 5 mg (860600P-5mg) pkg of 1 × 50 mg (860600P-50mg)
manufacturer/tradename	Avanti Polar Lipids 860600P
运输	dry ice
储存温度	?20℃
SMILES string	[H][C@](/C=C/CCCCCCCCCCCCC)(O)[C@@]([H])(N)COP([O-])(OCC[N+](C)(C)C)=O

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable