半岛bd体育手机客户端 说明
一般描述
HSP90AB1 (heat shock protein 90α family class B member 1) belongs to the Hsp90 family. It consists of major members-Hsp90α, Hsp90β, GRP94 (glucose-regulated protein 94) and Hsp75. It is located on chromosome 6p21. HSP90AB1is an ATP-dependent molecular chaperone, having a molecular weight of 90kDa. HSP90AA1 is located on human chromosome 14q32.31.
特异性
The antibody is reactive with both the constitutive and the inducible forms of HSP90. However, it does not bind to the native form of HSP90. It does not recognize HSP90 fromE. coliand yeast.
免疫原
heat shock protein 90 (HSP90) from the water moldAchlya ambisexualis
应用
Monoclonal Anti-Heat Shock Protein 90 antibody has been used in ovarian histomorphology, immunohistochemistry and western blotting.
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)
Western Blotting (1 paper)
生化/生理作用
HSP90AB1 (heat shock protein 90α family class B member 1) participates in signal transduction, protein folding and degradation, and morphological evolution. It is required for the transport of client proteins between the cytoplasm and nucleus. In lung adenocarcinoma patients, overexpression of HSP90AB1 in non-small cell lung cancer tissues results in imperfect clinical predictions. Suppression of this gene reduces the potential of endothelial cells to form tube structures.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
基本信息
| MDL编号 | MFCD02189140 |
| NACRES | NA.41 |
半岛bd体育手机客户端 性质
| 质量水平 | 200 |
| 生物来源 | mouse |
| 偶联物 | unconjugated |
| 抗体形式 | ascites fluid |
| antibody product type | primary antibodies |
| 克隆 | AC-16, monoclonal |
| 分子量 | antigen 88 kDa |
| 包含 | 15 mM sodium azide |
| species reactivity | Sf9 cell line, rat, wheat germ, rabbit, human, mouse, chicken,Achlya |
| 包装 | antibody small pack of 25 μL |
| technique(s) | microarray: suitable western blot: 1:1,000 using cultured human foreskin fibroblasts |
| 同位素/亚型 | IgG2b |
| UniProt登记号 | P07900 |
| 运输 | dry ice |
| 储存温度 | ?20℃ |
| Gene Information | human ... HSP90AA1(3320), HSP90AB1(3326) mouse ... Hsp90aa1(15519), Hsp90ab1(15516) |
安全信息
| 储存分类代码 | 12 - Non Combustible Liquids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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