半岛bd体育手机客户端 说明

一般描述

5-Bromo-2′-deoxyuridine 5′-triphosphate is used for incorporation into DNA for studying normal and tumor cell proliferation profiles.

应用

5-Bromo-2′-deoxyuridine 5′-triphosphate (5-BrdUTP) may be used as a labeling TdT substrate for terminal deoxynucleotidyl transferase (TdT) reactions or for DNA synthesis. BrdUTP is also used as an effective mutagenic agent. 5-BrdUTP labeling may be detected by immunological techniques or 5-BrdUTP may be derivitized by biotinylation or other methods for detection by fluorogenic or chromogenic methods.
5-Bromo-2′-deoxyuridine 5′-triphosphate sodium salt has been used:

• in the labelling of 3′-OH termini of fragmented DNA with double stranded breaks in african green monkey kidney cells
• to label cleaved DNA ends in apoptosis assay in avian tissue sections
• for incorporation into mice prostates for immunohistochemistry studies

包装

25 mg in poly bottle
1, 5 mg in glass bottle

基本信息

经验(实验)分子式	C9H14BrN2O14P3
分子量	547.04
MDL编号	MFCD00057405
PubChem化学物质编号	24891527
NACRES	NA.51

半岛bd体育手机客户端 性质

质量水平	200
生物来源	synthetic (organic)
测定	≥90%
形式	powder
溶解性	water: 50 mg/mL, clear, colorless to faintly yellow
储存温度	?20℃
SMILES string	[Na].OC1CC(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N2C=C(Br)C(=O)NC2=O
InChI	1S/C9H14BrN2O14P3.Na.H/c10-4-2-12(9(15)11-8(4)14)7-1-5(13)6(24-7)3-23-28(19,20)26-29(21,22)25-27(16,17)18;;/h2,5-7,13H,1,3H2,(H,19,20)(H,21,22)(H,11,14,15)(H2,16,17,18);;
InChI key	UWZGQOWZUSBZMC-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H315 - H319 - H335
预防措施声明	P302 + P352 - P305 + P351 + P338
危险分类	Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
个人防护装备	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges