半岛bd体育手机客户端 说明
应用
(S)-(?)-Sulpiride was used to study the effect of dopamine D2receptor function on activation of KCNQ potassium channels10and on depression-like behavior in ovariectomized female rats.11
包装
5, 10 g in poly bottle
生化/生理作用
(S)-(?)-Sulpiride or Levosulpiride blocks the inhibitory enteric D2receptors (neuronal and muscular). It has prokinetic activity and is effective in the treatment of functional dyspepsia and gastroparesis in insulin-dependent diabetes mellitus patients.7,8Since dopamine controls human sexual function, (S)-(?)-Sulpiride is reportedly effective in treatment of erectile dysfunctions.9
D2多巴胺受体拮抗剂;安定药。
特点和优势
This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
基本信息
经验(实验)分子式 | C15H23N3O4S |
分子量 | 341.43 |
MDL编号 | MFCD00055220 |
PubChem化学物质编号 | 24278709 |
NACRES | NA.77 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥98% (titration) |
mp | 183-186 ℃ (lit.) |
创始人 | Sanofi Aventis |
储存温度 | 2-8℃ |
SMILES string | CCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(N)(=O)=O |
InChI | 1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1 |
InChI key | BGRJTUBHPOOWDU-NSHDSACASA-N |
Gene Information | human ... DRD2(1813), DRD3(1814) rat ... Adra1a(29412), Drd2(24318), Drd3(29238), Htr1a(24473), Htr2a(29595) |
安全信息
储存分类代码 | 13 - Non Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich