半岛bd体育手机客户端 说明
应用
SMER28 may be used in mTOR-mediated signaling studies.
包装
5, 25 mg in glass bottle
生化/生理作用
SMER28 is a small molecule modulator of mammalian autophagy; enhances A53T alpha-synuclein clearance in PC-12 cells independent of rapamycin treatment; appears to act independent of the mTOR pathway, but combined treatment with saturating rapamycin concentration enhances the effect of either compound alone on A53T alpha-synuclein clearance; autophagy inducers may prove useful in the treatment of neurodegenerative and infectious diseases and cancer.
基本信息
| 经验(实验)分子式 | C11H10BrN3 |
| 分子量 | 264.12 |
| MDL编号 | MFCD02166825 |
| PubChem化学物质编号 | 329824598 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | >99% (HPLC) |
| 形式 | solid |
| 溶解性 | DMSO: >20 mg/mL H2O: insoluble |
| 储存温度 | 2-8℃ |
| SMILES string | Brc1ccc2ncnc(NCC=C)c2c1 |
| InChI | 1S/C11H10BrN3/c1-2-5-13-11-9-6-8(12)3-4-10(9)14-7-15-11/h2-4,6-7H,1,5H2,(H,13,14,15) |
| InChI key | BCPOLXUSCUFDGE-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 11 - Combustible Solids |
| WGK | WGK 3 |
| 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
Sigma-Aldrich
m.cnreagent.com
