半岛bd体育手机客户端 说明
包装
5, 25 mg in glass bottle
生化/生理作用
PF-04856264 is a potent, selective inhibitor of the human Nav1.7 voltage gated sodium channel (IC50= 28 nM). PF-04856264 blocks mouse Nav1.7 (IC50= 131 nM) but has low potency against the rat Nav1.7 channel (IC50= 4.2 mM).
基本信息
| 经验(实验)分子式 | C20H15N5O3S2 |
| 分子量 | 437.49 |
| MDL编号 | MFCD28124397 |
| PubChem化学物质编号 | 329825643 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to light brown |
| 溶解性 | DMSO: 10 mg/mL, clear |
| 储存温度 | 2-8℃ |
| SMILES string | O=S(C(C=C1)=CC(C#N)=C1OC2=CC=CC=C2C3=CC=NN3C)(NC4=NC=CS4)=O |
| InChI | 1S/C20H15N5O3S2/c1-25-17(8-9-23-25)16-4-2-3-5-19(16)28-18-7-6-15(12-14(18)13-21)30(26,27)24-20-22-10-11-29-20/h2-12H,1H3,(H,22,24) |
| InChI key | MKSKJVIBSRUWSZ-UHFFFAOYSA-N |
安全信息
| 象形图 |  |
| 警示用语： | Danger |
| 危险声明 | H301 |
| 预防措施声明 | P301 + P310 |
| 危险分类 | Acute Tox. 3 Oral |
| 储存分类代码 | 6.1D - Non-combustible, acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
Sigma-Aldrich
m.cnreagent.com
