NH125

半岛bd体育手机客户端 说明

包装

5, 25 mg in glass bottle
在氮气保护下封装。

生化/生理作用

NH125 exhibits anti-proliferation activity against many cancer cells. It also exhibits antibacterial effects by inhibiting bacterial histidine protein kinase.
NH125 is a novel plant histidine kinase inhibitor and selective mammalian eurkaryotic elongation factor-2 kinase (eEF-2K).

分析说明

IC₅₀= 60 nM for eEF-2 kinase vs protein kinase C (IC₅₀= 7.5 μM), protein kinase A (IC₅₀= 80 μM), and calmodulin-dependent kinase II IC₅₀> 100 μM).

基本信息

经验(实验)分子式	C27H45IN2
分子量	524.56
MDL编号	MFCD07370143
PubChem化学物质编号	329818598
NACRES	NA.77

半岛bd体育手机客户端 性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
颜色	white to off-white
mp	88.2-94.9 ℃
溶解性	DMSO: >20 mg/mL
储存温度	?20℃
SMILES string	[I-].CCCCCCCCCCCCCCCC[n+]1ccn(Cc2ccccc2)c1C
InChI	1S/C27H45N2.HI/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-28-23-24-29(26(28)2)25-27-20-17-16-18-21-27;/h16-18,20-21,23-24H,3-15,19,22,25H2,1-2H3;1H/q+1;/p-1
InChI key	RVWOHCBHAGBLLT-UHFFFAOYSA-M

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	dust mask type N95 (US), Eyeshields, Gloves