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M30 dihydrochloride

品牌
Sigma-Aldrich
CAS
64821-19-8
货号
SML0128
规格纯度
≥98% (HPLC)
价格
1202.81 *本价格含增值税费
促销
服务
  • 原厂保证
  • 包邮
  • 增值税票
数量
- +
半岛bd体育手机客户端 名称:
64821-19-8
M30 dihydrochloride
VAR10300 dihydrochloride
M-30 dihydrochloride
5-[N-methyl-N-propargylaminomethyl]-8-hydroxyquinoline dihydrochloride
半岛bd体育手机客户端 介绍:

半岛bd体育手机客户端 说明

应用

M30 dihydrochloride may be used in monamine oxidase-mediated cell signaling studies.

包装

5, 25 mg in glass bottle

生化/生理作用

M30 is a site-activated iron chelator and monoamine oxidase (MAO) inhibitor; with neuroprotective and anti-apoptotic activity. It is a multifunctional non-toxic, brain permeable iron chelator possessing a neuroprotective propargylamine moiety and an antioxidant-iron chelator moiety. M30 is a selective irreversible inhibitor of mitochondrial brain monoamine oxidases A and B (MAO-A and -B), providing for improved levels of neurotransmitters. It reduces oxidative damage and shows neuroprotective and neurorestorative effects in various neurodegenerative models of ALS, Alzheimer′s and Parkinson′s diseases, and is being investigated in other diseases where oxidative stress is a problem.

特点和优势

This compound is featured on the Dopamine and Norepinephrine Metabolism and Histamine Synthesis and Metabolism pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式 C14H14N2O · 2HCl
分子量 299.20
MDL编号 MFCD20488063
PubChem化学物质编号 329825178
NACRES NA.77

半岛bd体育手机客户端 性质

质量水平 100
测定 ≥98% (HPLC)
形式 powder
储存条件 desiccated
颜色 green-yellow
溶解性 DMSO, heptane and xylene: ≥21 mg/mL
储存温度 2-8℃
SMILES string Cl.Cl.CN(CC#C)Cc1ccc(O)c2ncccc12
InChI 1S/C14H14N2O.2ClH/c1-3-9-16(2)10-11-6-7-13(17)14-12(11)5-4-8-15-14;;/h1,4-8,17H,9-10H2,2H3;2*1H
InChI key XJNICPXVRPOSSO-UHFFFAOYSA-N

安全信息

象形图 GHS05GHS07
警示用语: Danger
危险声明 H302 - H318
预防措施声明 P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310
危险分类 Acute Tox. 4 Oral - Eye Dam. 1
储存分类代码 11 - Combustible Solids
WGK WGK 3
闪点(F) Not applicable
闪点(C) Not applicable

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