Desethylchloroquine

品牌

Sigma-Aldrich

CAS

1476-52-4

货号

SMB00963

包装型号

规格纯度

≥95% (HPLC)

价格

5063.47 元 *本价格含增值税费

促销

数量

- +

半岛bd体育手机客户端名称：

1476-52-4
Desethylchloroquine
4-[[1-Methyl-4-((ethylamino)butyl]amino)]-7-chloroquinoline
N-Desethyl chloroquine
N ⁴-(7-Chloro-4-quinolinyl)- N ¹-ethyl-1,4-pentanediamine
7-Chloro-4-{[4-(ethylamino)-1-methylbutyl]amino}quinoline
7-Chloro-4-(4- N-ethylamino-1-methylbutylamino)quinoline
Monodesethylchloroquine
N-Desethylchloroquine
Monodeethylchloroquine

半岛bd体育手机客户端介绍：

半岛bd体育手机客户端说明

一般描述

Desethylchloroquine is a metabolite of hydroxychloroquine and chloroquine. Hydroxychloroquine and chloroquine have antimalarial properties and are used as a therapeutic for rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and other inflammatory rheumatic diseases. They have also been in the spotlight due to their activity on patients with COVID-19, the disease caused by the SARS-CoV-2 virus. Hydroxychloroquine and chloroquine interfere with lysosomal activity and autophagy, interact with membrane stability and alter signalling pathways and transcriptional activity, which can result in modulation of cytokine production. Their mode of action is still emerging and their metabolism is of great interest.

应用

Application: Metabolomics research

基本信息

经验(实验)分子式	C₁₆H₂₂ClN₃
分子量	291.82
MDL编号	MFCD00871808

半岛bd体育手机客户端性质

质量水平	200
生物来源	synthetic
等级	research grade
测定	≥95% (HPLC)
形式	powder or crystals
technique(s)	HPLC: suitable
颜色	white to off-white
运输	wet ice
储存温度	2-8℃
SMILES string	ClC(C=C1)=CC2=C1C(NC(CCCNCC)C)=CC=N2
InChI	1S/C16H22ClN3/c1-3-18-9-4-5-12(2)20-15-8-10-19-16-11-13(17)6-7-14(15)16/h6-8,10-12,18H,3-5,9H2,1-2H3,(H,19,20)
InChI key	MCYUUUTUAAGOOT-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable