半岛bd体育手机客户端 说明
一般描述
Bisdesethylchloroquine is an immediate metabolite of hydroxychloroquine and chloroquine. These are antimalarial drugs used clinically in the treatment of rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and other inflammatory rheumatic diseases. These drugs interfere with lysosomal activity and autophagy, interact with membrane stability and alter signalling pathways and transcriptional activity, which can result in modulation of cytokine production and certain co-stimulatory molecules. Hydroxychloroquine and chloroquine mode(s) of action are still emerging and their metabolism are of great interest. Metabolic Pathway: Cytochrome P450 drug.
应用
Metabolomics research
基本信息
| 经验(实验)分子式 | C14H18ClN3· xHCl |
| 分子量 | 263.77 (free base basis) |
| MDL编号 | MFCD00871854 |
半岛bd体育手机客户端 性质
| 质量水平 | 200 |
| 测定 | ≥95 % (HPLC) |
| 形式 | solid |
| 储存温度 | 2-8℃ |
Sigma-Aldrich
m.cnreagent.com
