半岛bd体育手机客户端 说明
一般描述
A cell-permeable, thiazolidinone compound that specifically inhibits c-Myc-Max interaction, thereby preventing the transactivation of c-Myc targeted gene expression. Shown to inhibit tumor cell growth in a c-Myc-dependent manner bothin vitroandin vivo(Effective concentration: 64 ?M using c-Myc-transfected Rat1a fibroblasts).
A cell-permeable thiazolidinone compound that specifically inhibits the c-Myc-Max interaction, thereby preventing the transactivation of c-Myc target gene expression. Shown to inhibit tumor cell growth in a c-Myc-dependent manner bothin vitroandin vivo(64 μM using c-Myc transfected Rat1a fibroblasts).
包装
10 mg in Plastic ampoule
Packaged under inert gas
生化/生理作用
Cell permeable: yes
Product does not compete with ATP.
Reversible: no
Primary Target
c-Myc
警告
Toxicity: Carcinogenic / Teratogenic (D)
重悬
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
其他说明
Yin, X., et al. 2003.Oncogene22,6151.
法律信息
Sold under license of U.S. Patent 7,026,343.
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
基本信息
经验(实验)分子式 | C12H11NOS2 |
分子量 | 249.35 |
MDL编号 | MFCD00758517 |
半岛bd体育手机客户端 性质
质量水平 | 100 |
测定 | ≥95% (sum of two isomers, HPLC) |
形式 | solid |
manufacturer/tradename | Calbiochem? |
储存条件 | OK to freeze protect from light |
颜色 | yellow |
溶解性 | DMSO: 200 mg/mL |
运输 | ambient |
储存温度 | 2-8℃ |
安全信息
象形图 | |
警示用语: | Warning |
危险声明 | H317 - H319 |
预防措施声明 | P261 - P264 - P272 - P280 - P302 + P352 - P305 + P351 + P338 |
危险分类 | Eye Irrit. 2 - Skin Sens. 1 |
储存分类代码 | 11 - Combustible Solids |
WGK | WGK 3 |
闪点(F) | Not applicable |
闪点(C) | Not applicable |
Sigma-Aldrich