半岛bd体育手机客户端 说明
包装
5, 25 mg in glass bottle
生化/生理作用
U-104 is an inhibitor of CA IX that binds only to CA IX under hypoxic conditions in vivo. The binding results in significant inhibition of tumor growth and metastasis formation in both spontaneous and experimental models of metastasis. U-104 reduces the medium acidity by inhibiting the catalytic activity of the CA IX. It binds specifically only to hypoxic cells expressing CA IX.
基本信息
| 经验(实验)分子式 | C13H12FN3O3S |
| 分子量 | 309.32 |
| MDL编号 | MFCD00159265 |
| PubChem化学物质编号 | 329825375 |
| NACRES | NA.77 |
半岛bd体育手机客户端 性质
| 质量水平 | 100 |
| 测定 | ≥98% (HPLC) |
| 形式 | powder |
| 颜色 | white to beige |
| 溶解性 | DMSO: >15 mg/mL |
| 储存温度 | 2-8℃ |
| SMILES string | O=C(NC1=CC=C(S(N)(=O)=O)C=C1)NC2=CC=C(F)C=C2 |
| InChI | 1S/C13H12FN3O3S/c14-9-1-3-10(4-2-9)16-13(18)17-11-5-7-12(8-6-11)21(15,19)20/h1-8H,(H2,15,19,20)(H2,16,17,18) |
| InChI key | YJQZNWPYLCNRLP-UHFFFAOYSA-N |
安全信息
| 储存分类代码 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| 闪点(F) | Not applicable |
| 闪点(C) | Not applicable |
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